Battling Aspergillus: The Synergistic Power of Statin Combinations
Aspergillus fungi cause severe respiratory infections that are quite often fatal in nature. Azole-based drugs are commonly prescribed for treating chronic as well as invasive pulmonary aspergillosis. However, the emergence of azole resistance in A. fumigatus is a matter of concern, as it can result in treatment failure. Researchers investigated the potential of statins, like pitavastatin, traditionally used to control blood lipid levels, in combination with azoles to effectively mitigate fungal activity in silkworm models.