Bis-Pseudoindoxyls: A New Class of Single Benzene-Based Fluorophores for Bioimaging Applications
2026.01.14
Research
Fluorescent dyes enable the visualization of biomolecular localization and dynamics in living systems. To date, no single benzene-based fluorophores with absorption and emission at wavelengths above 600 nm, the ideal wavelength for bioimaging, have been developed. To address this challenge, researchers from Japan have developed bis-pseudoindoxyls. Owing to its unique red-shifted absorption and fluorescence properties, this dye holds promise for applications in red-light-based bioimaging studies.
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Single benzene-based fluorophores with absorption wavelengths above 600 nm are ideal for bioimaging. Recently, scientists from Japan have developed bis-pseudoindoxyls, which exhibit red-region absorption and emission. This compact fluorophore is ideal for long-term live-cell imaging of lipid droplets in the red spectral region.